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In-Vitro and In-Vivo Models for Posttraumatic Disc Degeneration There is currently no genuine in-vivo model for posttraumatic disc degeneration (PTDD) because of ethical considerations and questionable reproducibility

Muscle growth (hypertrophy) occurs when resistance training creates microscopic damage to muscle fibers

In cell and tissue models, Epithalon upregulates telomerase activity, maintains telomere length, and modulates aging-related gene expression (p16, p21) to delay senescence

These findings support using the antioxidant agent Epitalon as a promising therapeutic strategy for DR to improve retinal wound healing compromised by hyperglycemia

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